Microscope slides are frequently used as standard substrates in biochip production. In contrast to DNA chips which, due to the robustness of DNA, are relatively easy to manufacture, protein biochips are much more delicate. The main reason is that proteins can't be immobilized on the same types of materials, for they are extremely sensitive to the physical and chemical properties of the particular substrate. In addition protein biochip surfaces must be bioinert and have to provide much higher immobilization capacities than DNA chips do. As our sensorchip surfaces meet the above criteria, we offer them on microcope slides too.

Coatings for Protein Biochips
Planar coatings
XanTec's planar coatings are extremely dense and practically defect-free. The atomically homogeneous surfaces have thicknesses in the low nm range. Therefore, they are perfectly suited for interaction experiments where well-defined surface properties are more important than a maximized immobilization capacity. In spite of their two-dimensional nature, the saccharide based coatings exhibit a very good stabilization against non-specific interactions.

Slides for DNA analysis or further modification
The surfaces listed below were developed with respect to maximized functional group densities. They are advantageous for solid-phase chemistry and work as a support for DNA arrays. As they can exhibit considerable non-specific interactions, they should not be used for protein biochip purposes.